USING SEX DIFFERENCES IN AGING IN LABORATORY ANIMALS TO UNDERSTAND HUMAN SEX DIFFERENCES

Aging: Manipulating Sex Differences

The life histories of animals are marked by two pervasive characteristics — nearly all animals reproduce sexually, and virtually all exhibit the hallmarks of physiological deterioration (i.e. senescence) with advancing age. While some animal species are hermaphroditic, many — including ourselves — are characterized by distinct sexual entities (gonochorism); individuals are either male or female...

Sex differences in human gregariousness

Research on human sociality rarely includes kinship, social structure, sex, and familiarity, even though these variables influence sociality in non-human primates. However, cross-cultural ethnographic and observational studies with humans indicate that, beginning after age 5 years, males and females form differing social structures with unrelated individuals in a community. Specifically, compar...

sex differences in acute myocardial infarction

Sex Differences Sex Chromosome Complement Contributes to Sex Differences in Bradycardic Baroreflex Response

To investigate whether sex chromosome complement modulates bradycardic baroreflex response and contributes to the angiotensin II–bradycardic baroreflex sex differences, we used the four core genotype mouse model in which the effect of gonadal sex and sex chromosome complement is dissociated, allowing comparisons of sexually dimorphic traits among XX and XY females, as well as in XX and XY males...

Sex differences in partner preferences in humans and animals.

A large number of morphological, physiological and behavioural traits are differentially expressed by males and females in all vertebrates including humans. These sex differences, sometimes, reflect the different hormonal environment of the adults, but they often remain present after subjects of both sexes are placed in the same endocrine conditions following gonadectomy associated or not with ...